Accession VIRO:0000507
Synonym(s)CAMP factor
DefinitionCAMP factor (cfb) is a pore-forming toxin that oligomerizes to generate discrete pores in target cells, using the carbohydrate core of GPI-anchored proteins as a membrane receptor. However, evidence shows that while it does have pore-forming function, it is not essential for pathogenesis.
Classification10 ontology terms | Show
Parent Term(s)3 ontology terms | Show

Hensler ME, et al. 2007. Microb Pathog 44(1): 84-88. CAMP factor is not essential for systemic virulence of Group B Streptococcus. (PMID 17870297)

Rajagopal L. 2009. Future Microbiol 4(2): 201-221. Understanding the regulation of Group B Streptococcal virulence factors. (PMID 19257847)

Lang S, et al. 2003. J. Biol. Chem. 278(40):38167-73 Characterization of Streptococcus agalactiae CAMP factor as a pore-forming toxin. (PMID 12835325)

Private model - RGI is not currently using this model.