beta-lactam potentiator

Accession ARO:3004564
DefinitionBeta-lactam potentiators are a type of resistance-modifying agent (RMA) which do not impose antibacterial or beta-lactamase inhibitory ability on their own, but improve the performance of antibiotic drugs, specifically beta-lactams.
Classification1 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show

Zhu Y, et al. 2017. Eur J Med Chem 125:130-142 Tetracyclic indolines as a novel class of β-lactam-selective resistance-modifying agent for MRSA. (PMID 27657810)

Farha MA, et al. 2018. ACS Infect Dis 4(3):382-390 Bicarbonate Alters Bacterial Susceptibility to Antibiotics by Targeting the Proton Motive Force. (PMID 29264917)