ramoplanin [Antibiotic]

Download Sequences


Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3004567
DefinitionRamoplanin is a glycolipodepsipeptide antibiotic derived from gram-positive Actinoplanes used to treat infection with Clostridioides difficile.
SMILESCC(C)C/C=C/C=C\C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]1C(=O)N[C@H](c2ccc(O)cc2)C(=O)N[C@H](CCCN)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](c2ccc(O)cc2)C(=O)N[C@H](c2ccc(O)cc2)C(=O)N[C@@H]([C@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CCCN)C(=O)N[C@@H](c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)cc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](c2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C)C(=O)N[C@@H](c2ccc(O)c(Cl)c2)C(=O)O[C@@H]1C(N)=O
PubChem16132338
CHEBI29670
ChEMBLCHEMBL2368737
Drug Classpeptide antibiotic, nonribosomal peptide antibiotics
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Publications

Cheng M, et al. 2014. Antimicrob. Agents Chemother. 58(11):6819-27 Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus. (PMID 25182650)
Curator Acknowledgements
Curator Description Most Recent Edit