Ribosomal protein mutation conferring resistance to pleuromutilin antibiotics [AMR Gene Family]

Accession ARO:3005082
DefinitionRibosomal protein mutations that interfere with the rRNA conformation at the active site thus conferring antibiotic resistance.
Drug Classpleuromutilin antibiotic
Resistance Mechanismantibiotic target alteration
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class pleuromutilin antibiotic [Drug Class]
+ antibiotic resistant gene variant or mutant
1 ontology terms | Show

Killeavy EE, et al. 2020. Antibiotics (Basel) 9(6): Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus. (PMID 32526926)