baicalin [Adjuvant]

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Accession ARO:3007329
DefinitionBaicalin is a flavonoid compound that is able to inhibit the activity of tetK and MsrA antibiotic efflux pumps. It is also able to inhibit the formation of bacterial biofilms and disrupt quorum sensing.
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Parent Term(s)3 ontology terms | Show

Wang J, et al. 2019. Front Microbiol 10:2800 Baicalin Inhibits Biofilm Formation and the Quorum-Sensing System by Regulating the MsrA Drug Efflux Pump in Staphylococcus saprophyticus. (PMID 31921008)

Luo J, et al. 2017. PLoS One 12(4):e0176883 Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model. (PMID 28453568)