thioridazine [Adjuvant]

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Accession ARO:3007337
DefinitionThioridazine is a phenothiazine drug used in the treatment of schizophrenia and psychosis. It is also able to inhibit mycobacterial antibiotic efflux pumps and the formation of bacterial biofilms.
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Parent Term(s)2 ontology terms | Show

Ruth MM, et al. 2020. Antimicrob Agents Chemother 64(7): Thioridazine Is an Efflux Pump Inhibitor in Mycobacterium avium Complex but of Limited Clinical Relevance. (PMID 32312774)

Kvist M, et al. 2008. Appl Environ Microbiol 74(23): 7376-7382. Inactivation of efflux pumps abolishes bacterial biofilm formation. (PMID 18836028)