Accession ARO:3007407
DefinitionA family of aminoglycoside O-nucleotidyltransferase enzymes which inactivate streptomycin and spectinomycin by catalyzing the transfer of an AMP group from an ATP substrate, thereby conferring resistance to these compounds. These enzymes modify the 3''-hydroxyl position of streptomycin and the 9-hydroxyl position of spectinomycin.
AMR Gene FamilyANT(3'')
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification10 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ ANT(3'') [AMR Gene Family]
2 ontology terms | Show