monensin [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3007484
DefinitionMonensin is an ionophore antibiotic isolated from Streptomyces cinnamonensis with very strong antibacterial and antiparasitic effects.
SMILESCC[C@@]1([C@@H]2O[C@@H]([C@H]3O[C@@](O)(CO)[C@H](C)C[C@@H]3C)C[C@@H]2C)CC[C@H]([C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C(=O)O)O3)O2)O1
PubChem441145
ChEMBLCHEMBL256105
Drug Classionophore with antibiotic activity
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Publications

SeƧme M, et al. 2023. Med Oncol 40(7):187 Investigation of the TLR4 and IRF3 signaling pathway-mediated effects of monensin in colorectal cancer cells. (PMID 37219624)

Curator Acknowledgements
Curator Description Most Recent Edit