ionophore with antibiotic activity [Drug Class]

Accession ARO:3005163
DefinitionIonophores are chemical entities which reversibly bind ions. Many ionophores display antibacterial and antifungal properties. An ionophore will bind and transport ions through a cell membrane, thereby potentially disrupting membrane potential and modifying permeability.
Classification1 ontology terms | Show
Parent Term(s)1 ontology terms | Show
6 ontology terms | Show
+ narasin [Antibiotic]
+ monensin [Antibiotic]
+ nigericin [Antibiotic]
+ salinomycin [Antibiotic]
+ pyrrolomycin antibiotic
+ Calcimycin [Antibiotic]

Bush K, et al. 2012. Rev Sci Tech 31(1):43-56 Antimicrobial agents targeting bacterial cell walls and cell membranes. (PMID 22849267)