| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3007772 |
| Definition | Valinomycin is a depsipeptide antibiotic which selectively translocates potassium across biologic membranes. This potassium ionophore was observed to inhibit phytohemagglutinin-stimulated blastogenesis and proliferation in human lymphocytes. |
| SMILES | CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@@H](C(C)C)NC(=O)[C@@H](C(C)C)OC(=O)[C@H](C(C)C)NC(=O)[C@H](C)OC(=O)[C@@H](C(C)C)NC(=O)[C@@H](C(C)C)OC(=O)[C@H](C(C)C)NC(=O)[C@H](C)OC(=O)[C@@H](C(C)C)NC(=O)[C@@H](C(C)C)OC1=O |
| PubChem | 3000706 |
| ChEBI | 28545 |
| ChEMBL | CHEMBL223643 |
| Drug Class | ionophore with antibiotic activity |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + ionophore with antibiotic activity [Drug Class] |
| Publications | Daniele RP, et al. 1976. Proc Natl Acad Sci U S A 73(10):3599-602 A potassium ionophore (valinomycin) inhibits lymphocyte proliferation by its effects on the cell membrane. (PMID 1068473) |
| Curator | Description | Most Recent Edit |
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