| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3007503 |
| Definition | Anidulafungin is an antibiotic, particularly antifungal, derived from echinocandins. It exhibits strong antifungal action against a variety of Candida spp. and Aspergillus spp., including those that are resistant to amphotericin B and triazole. |
| SMILES | CCCCCOc1ccc(-c2ccc(-c3ccc(C(=O)N[C@H]4C[C@@H](O)[C@@H](O)NC(=O)[C@@H]5[C@@H](O)[C@@H](C)CN5C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@H](O)[C@@H](O)c5ccc(O)cc5)NC(=O)[C@@H]5C[C@@H](O)CN5C(=O)[C@H]([C@@H](C)O)NC4=O)cc3)cc2)cc1 |
| PubChem | 166548 |
| CHEBI | 55346 |
| ChEMBL | CHEMBL264241 |
| Drug Class | echinocandin antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + echinocandin antibiotic [Drug Class] |
| Sub-Term(s) | 12 ontology terms | Show + Candida glabrata FKS2 with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Candida parapsilosis Erg3 with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Pichia kudriavzevii Fks1 beta-1,3-glucan synthase with mutations associated with resistance to anidulafungin confers_resistance_to_antibiotic + Candida glabrata FKS1 with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Candida albicans FKS1 with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Candida auris FKS1 beta-1,3-glucan synthase with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Saccharomyces cerevisiae FKS1 beta-1,3-D-glucan synthase with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Candida dubliniensis FKS1 beta-1,3-glucan synthase with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Candida metapsilosis FKS1 beta-1,3-glucan with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Candida parapsilosis FSK1 beta-1,3-D-glucan synthase with mutations associated with resistance to anidulafungin confers_resistance_to_antibiotic + Candida tropicalis FKS1 beta-1,3-glucan synthase with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic + Kluyveromyces marxianus FKS1 beta-1,3-glucan synthase with mutations conferring resistance to anidulafungin confers_resistance_to_antibiotic |
| Publications | Murdoch D, et al. 2004. Drugs 64(19):2249-58; discussion 2259-60 Anidulafungin. (PMID 15456342) |
| Curator | Description | Most Recent Edit |
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