amphotericin B [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3007504
DefinitionAmphotericin B is an antibiotic, particularly antifungal, derived from polyene. It exhibits strong antifungal action against a variety of fungi species and is typically considered the gold standard of antifungals.
SMILESC[C@@H]1[C@H](O)[C@@H](C)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@H]2O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@H]1C)C[C@H](O)[C@H]2C(=O)O
PubChem5280965
ChEBI2682
CAS1397-89-3
ChEMBLCHEMBL267345
Drug Classpolyene antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ polyene antibiotic [Drug Class]
Sub-Term(s)
1 ontology terms | Show
+ antifungal resistance-associated MSH2 [AMR Gene Family] confers_resistance_to_antibiotic
Publications

Cavassin FB, et al. 2021. Infect Dis Ther 10(1):115-147 Sixty years of Amphotericin B: An Overview of the Main Antifungal Agent Used to Treat Invasive Fungal Infections. (PMID 33523419)

Curator Acknowledgements
Curator Description Most Recent Edit