5-fluorocytosine [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3009160
DefinitionAn antifungal compound that is converted into fluorouracil inside cells, thereby impairing the synthesis of proteins and DNA. This drug should almost always be used in combination with amphotericin B for systemic fungal infections, but the ratio is important since flucytosine can increase the toxicity of amphotericin B and vice versa. Flucytosine is typically indicated for Candida and Cryptococcus infections.
SMILESNC1=C(F)C=NC(=O)N1
PubChem3366
ChEMBLCHEMBL1463
ChEBI5100
CAS2022-85-7
Drug Classnucleoside antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ nucleoside antibiotic [Drug Class]
Curator Acknowledgements
Curator Description Most Recent Edit