| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3009186 |
| Definition | Boscalid is a broad spectrum fungicide that is a succinate dehydrogenase (specifically complex II in the mitochondria) inhibitor. It ultimately blocks electron transport and ATP production in the mitochondrial electron transport chain, disrupting fungal respiration and leads to cell death or halted growth. |
| SMILES | C1=CC=C(C(=C1)C2=CC=C(C=C2)Cl)NC(=O)C3=C(N=CC=C3)Cl |
| CAS | 188425-85-6 |
| ChEMBL | CHEMBL1076544 |
| CHEBI | 81822 |
| PubChem | 213013 |
| Drug Class | fungal succinate dehydrogenase inhibitor |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + fungal succinate dehydrogenase inhibitor [Drug Class] |
| Sub-Term(s) | 3 ontology terms | Show + Aspergillus fumigatus beta-tubulin with mutations conferring resistance to boscalid confers_resistance_to_antibiotic + Aspergillus fumigatus Cyp51A with mutations conferring resistance to benomyl confers_resistance_to_antibiotic + Aspergillus fumigatus Cyp51A with mutations conferring resistance to boscalid confers_resistance_to_antibiotic |
| Publications | Yin YN, et al. 2011. Phytopathology 101(8):986-95 Molecular characterization of boscalid resistance in field isolates of Botrytis cinerea from apple. (PMID 21469935) De Miccolis Angelini RM, et al. 2014. Pest Manag Sci 70(12):1884-93 Molecular characterisation and detection of resistance to succinate dehydrogenase inhibitor fungicides in Botryotinia fuckeliana (Botrytis cinerea). (PMID 24481672) Veloukas T, et al. 2011. Plant Dis 95(10):1302-1307 Detection and Molecular Characterization of Boscalid-Resistant Botrytis cinerea Isolates from Strawberry. (PMID 30731698) Malandrakis AA, et al. 2022. Pestic Biochem Physiol 183:105058 Fungicide resistance frequencies of Botrytis cinerea greenhouse isolates and molecular detection of a novel SDHI resistance mutation. (PMID 35430062) |
| Curator | Description | Most Recent Edit |
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