epoxiconazole [Antibiotic]

Download Sequences


Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3009191
DefinitionEpoxiconazole was introduced in 1990 as a broad-spectrum fungicide with long-lasting activity. Even though epoxiconazole is produced and commercialized as a racemic compound, not surprisingly, a recent publication indicates that the optically pure (2S,3R) enantiomer of epoxiconazole is much more active against pathogenic fungi than its (2R,3S)-enantiomer, whereas the plant growth regulatory activity mainly rests in the (2R,3S)-enantiomer.
SMILESC1=CC=C(C(=C1)[C@@H]2[C@@](O2)(CN3C=NC=N3)C4=CC=C(C=C4)F)Cl
PubChem107901
CAS133855-98-8
Drug Classtriazole antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ triazole antibiotic [Drug Class]
Publications

Chen Y, et al. 2018. Antimicrob Agents Chemother 62(5): Elevated MIC Values of Imidazole Drugs against Aspergillus fumigatus Isolates with TR34/L98H/S297T/F495I Mutation. (PMID 29507067)

Curator Acknowledgements
Curator Description Most Recent Edit