fenbuconazole [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3009212
DefinitionFenbuconazole is a triazole fungicide intended for use as an agricultural and horticultural fungicide spray. It is a systemic protectant and curative which acts by inhibiting sterol biosynthesis in fungi. Fenbuconazole is rapidly absorbed and eliminated, mainly in the faeces through significant biliary excretion; there was no evidence of significant retention in tissues. Fenbuconazole was of low acute toxicity when administered orally (LD50 > 2000 mg/kg bw), dermally (LD50 > 5000 mg/kg bw), or by inhalation (LC50 > 2.1 mg/litre air). It was not irritating to the skin or eyes.
SMILESC1=CC=C(C=C1)C(CCC2=CC=C(C=C2)Cl)(CN3C=NC=N3)C#N
PubChem86138
CAS114369-43-6
CHEBI83920
ChEMBLCHEMBL1879687
Drug Classazole antibiotic, triazole antifungal
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ triazole antifungal [Drug Class]
Sub-Term(s)
1 ontology terms | Show
Publications

Reynolds KL, et al. 1997. Plant Dis 81(2):163-166 Sensitivity of Cladosporium caryigenum to Propiconazole and Fenbuconazole. (PMID 30870889)

Curator Acknowledgements
Curator Description Most Recent Edit