| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3009408 |
| Definition | Flusilazole is an organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by p-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1H-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops. It has a role as a xenobiotic, an environmental contaminant, an EC 1.14.13.70 (sterol 14 alpha-demethylase) inhibitor and an antifungal agrochemical. It is a member of monofluorobenzenes, a member of triazoles, and an organosilicon compound. |
| SMILES | C[Si](CN1C=NC=N1)(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F |
| CAS | 85509-19-9 |
| ChEMBL | CHEMBL1900522 |
| PubChem | 73675 |
| Drug Class | azole antibiotic, triazole antifungal |
| Classification | 3 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + triazole antifungal [Drug Class] |
| Sub-Term(s) | 4 ontology terms | Show + Zymoseptoria tritici Cyp51 with mutations conferring resistance to flusilazole confers_resistance_to_antibiotic + Pyrenopeziza brassicae Cyp51 with mutations conferring resistance to flusilazole confers_resistance_to_antibiotic + Tapesia acuformis Cyp51 with mutations conferring resistance to flusilazole confers_resistance_to_antibiotic + Tapesia yallundae Cyp51 with mutations conferring resistance to flusilazole confers_resistance_to_antibiotic |
| Publications | Wang Y, et al. 2021. Pestic Biochem Physiol 171:104722 Baseline sensitivity and action mechanism of the sterol demethylation inhibitor flusilazole to Valsa mali. (PMID 33357544) |
| Curator | Description | Most Recent Edit |
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