Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:0000009 |
Definition | Tunicamycin is mixture of homologous nucleoside antibiotics that block the reaction of UDP-N-acetylglucosamine and dolichyl phosphate in the first step of glycoprotein synthesis. |
SMILES | CC(=O)N[C@H]1[C@@H](O[C@@H]2O[C@H](CC(O)[C@H]3O[C@@H](n4ccc(=O)[nH]c4=O)[C@H](O)[C@@H]3O)[C@H](O)[C@H](O)[C@H]2NC(=O)/C=C/CC(C)C)O[C@H](CO)[C@@H](N)[C@@H]1O |
PubChem | 5354023 |
ChEBI | 29699 |
CAS | 11089-65-9 |
ChEMBL | CHEMBL505513 |
Drug Class | nucleoside antibiotic |
Classification | 2 ontology terms | Show |
Parent Term(s) | 2 ontology terms | Show |
Sub-Term(s) | 2 ontology terms | Show + tmrB confers_resistance_to_antibiotic + tunicamycin resistance protein [AMR Gene Family] confers_resistance_to_antibiotic |
Publications | Noda Y, et al. 1992. J Bacteriol 174(13): 4302-4307. TmrB protein, responsible for tunicamycin resistance of Bacillus subtilis, is a novel ATP-binding membrane protein. (PMID 1624425) |
Curator | Description | Most Recent Edit |
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