ristocetin [Antibiotic]

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Accession ARO:3000022
DefinitionRistocetin is a glycopeptide antibiotic similar to vancomycin but positively charged. It is not used clinically because it induces platelet agglutination.
Drug Classglycopeptide antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show
+ acyl-D-alanyl-D-alanine targeted_by_antibiotic

Coller BS and Gralnick HR. 1977. J Clin Invest 60(2): 302-312. Studies on the mechanism of ristocetin-induced platelet agglutination. Effects of structural modification of ristocetin and vancomycin. (PMID 17620)

Reynolds PE. 1989. Eur J Clin Microbiol Infect Dis 8(11): 943-950. Structure, biochemistry and mechanism of action of glycopeptide antibiotics. (PMID 2532132)