| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3000022 |
| Definition | Ristocetin is a glycopeptide antibiotic similar to vancomycin but positively charged. It is not used clinically because it induces platelet agglutination. |
| SMILES | Cc1c(O)cc2cc1Oc1cc(ccc1O)[C@@H](N)C(=O)N[C@H]1C(=O)N[C@@H]2C(=O)N[C@H]2C(=O)N[C@H]3C(=O)N[C@H](C(=O)N[C@@H](C(=O)O)c4cc(O)cc(O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)c4-c4cc3ccc4O)[C@H](O[C@H]3C[C@@H](N)[C@@H](O)[C@H](C)O3)c3ccc(cc3)Oc3cc2cc(c3O[C@H]2O[C@@H](CO[C@H]3O[C@H](C)[C@@H](O)[C@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)Oc2ccc(cc2)[C@H]1O |
| PubChem | 16204749 |
| ChEBI | 85129 |
| CAS | 1404-55-3 |
| ChEMBL | CHEMBL1095986 |
| Drug Class | glycopeptide antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + glycopeptide antibiotic [Drug Class] |
| Sub-Term(s) | 1 ontology terms | Show + acyl-D-alanyl-D-alanine targeted_by_antibiotic |
| Publications | Coller BS and Gralnick HR. 1977. J Clin Invest 60(2): 302-312. Studies on the mechanism of ristocetin-induced platelet agglutination. Effects of structural modification of ristocetin and vancomycin. (PMID 17620) Reynolds PE. 1989. Eur J Clin Microbiol Infect Dis 8(11): 943-950. Structure, biochemistry and mechanism of action of glycopeptide antibiotics. (PMID 2532132) |
| Curator | Description | Most Recent Edit |
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