SME beta-lactamase [AMR Gene Family]

Accession ARO:3000055
DefinitionSME beta-lactamases are chromosome-mediated class A beta-lactamases that hydrolyze carbapenems in Serratia marcescens.
Drug Classcarbapenem
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ class A beta-lactamase
Sub-Term(s)
5 ontology terms | Show
Publications

Naas T, et al. 1994. Antimicrob Agents Chemother 38(6): 1262-1270. Cloning and sequence analysis of the gene for a carbapenem-hydrolyzing class A beta-lactamase, Sme-1, from Serratia marcescens S6. (PMID 8092824)