antibiotic A47934 [Antibiotic]

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Accession ARO:3000117
DefinitionA47934 is an 'aglycone' glycopeptide antibiotic produced by Streptomyces toyocaensis. It is a teicoplanin-like glycopeptide.
Drug Classglycopeptide antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show
+ acyl-D-alanyl-D-alanine targeted_by_antibiotic

Hadatsch B, et al. 2007. Chem Biol 14(9): 1078-1089. The biosynthesis of teicoplanin-type glycopeptide antibiotics: assignment of p450 mono-oxygenases to side chain cyclizations of glycopeptide a47934. (PMID 17884639)

Marshall CG and Wright GD. 1997. FEMS Microbiol Lett 157(2): 295-299. The glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009 has both D-alanyl-D-alanine and D-alanyl-D-lactate ligases. (PMID 9435111)

Lamb SS, et al. 2006. Chem Biol 13(2): 171-181. Biosynthesis of sulfated glycopeptide antibiotics by using the sulfotransferase StaL. (PMID 16492565)

Pootoolal J, et al. 2002. Proc Natl Acad Sci U S A 99(13): 8962-8967. Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009. (PMID 12060705)