| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3000184 |
| Definition | Chloroeremomycin is a vancomycin-like glycopeptide, with three sugars instead of two in vancomycin and balhimycin. Chloroeremomycin dimerizes and binds to the terminus of peptidoglycan precursors. |
| SMILES | CN[C@H](CC(C)C)C(=O)N[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]2C(=O)N[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)O)c4cc(O)cc(O)c4-c4cc3ccc4O)[C@H](O[C@H]3C[C@](C)(N)[C@@H](O)[C@H](C)O3)c3ccc(c(Cl)c3)Oc3cc2cc(c3O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@H]2C[C@](C)(N)[C@@H](O)[C@H](C)O2)Oc2ccc(cc2Cl)[C@H]1O |
| PubChem | 445806 |
| ChEBI | 29556 |
| CAS | 118395-73-6 |
| ChEMBL | CHEMBL1688951 |
| Drug Class | glycopeptide antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + glycopeptide antibiotic [Drug Class] |
| Sub-Term(s) | 1 ontology terms | Show + acyl-D-alanyl-D-alanine targeted_by_antibiotic |
| Publications | van Wageningen AM, et al. 1998. Chem Biol 5(3): 155-162. Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic. (PMID 9545426) Chen H, et al. 2000. Proc Natl Acad Sci U S A 97(22): 11942-11947. Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. (PMID 11035791) Shiozawa H, et al. 2002. J Am Chem Soc 124(15): 3914-3919. Cooperative binding interactions of glycopeptide antibiotics. (PMID 11942828) |
| Curator | Description | Most Recent Edit |
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