ANT(4') [AMR Gene Family]

Accession ARO:3000229
Synonym(s)aadD ant(4',4'')
DefinitionA category of aminoglycoside O-nucleotidyltransferase enzymes with modification regiospecificity based at the 4'-hydroxyl group of the respective antibiotic. These enzymes inactivate aminoglycoside antibiotics by transfer of an AMP group from an ATP substrate to the 4-hydroxyl group of the compound.
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification8 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ aminoglycoside nucleotidyltransferase (ANT)
+ confers_resistance_to_drug_class aminoglycoside antibiotic [Drug Class]
2 ontology terms | Show