Accession ARO:3007404
DefinitionA family of aminoglycoside 4'-O-nucleotidyltransferase enzymes which inactivate amikacin & tobramycin, but not dibekacin, by catalyzing the transfer of an AMP group from an ATP substrate, thereby conferring resistance to these compounds.
AMR Gene FamilyANT(4')
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification10 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ ANT(4') [AMR Gene Family]
2 ontology terms | Show