antibiotic resistant DNA topoisomerase subunit gyrA

Accession ARO:3000273
DefinitionPoint mutations in gyrA confer antibiotic resistance by preventing drugs from binding the alpha-subunit of gyrase, essential for DNA supercoiling.
Resistance Mechanismantibiotic target alteration
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
2 ontology terms | Show
+ fluoroquinolone resistant gyrA [AMR Gene Family]
+ triclosan resistant gyrA [AMR Gene Family]