antibiotic resistant DNA topoisomerase subunit parC

Accession ARO:3000274
DefinitionPoint mutations in parC confer antibiotic resistance by preventing drugs from binding the parC subunit of topoisomerase IV, essential for DNA decatanation and relaxation.
Resistance Mechanismantibiotic target alteration
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
1 ontology terms | Show
+ fluoroquinolone resistant parC [AMR Gene Family]