antibiotic sensitive DNA topoisomerase subunit parC

Accession ARO:3003256
DefinitionParC is a subunit of topoisomerase IV, which decatenates and relaxes DNA to allow access to genes for transcription or translation. Targeting topoisomerase IV inhibits DNA synthesis, and may also lead to double-stranded cell breaks.
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
2 ontology terms | Show

Reece RJ and Maxwell A. 1991. Crit Rev Biochem Mol Biol 26(3-4): 335-375. DNA gyrase: structure and function. (PMID 1657531)