Fluoroquinolone sensitive parC

Accession ARO:3000735
DefinitionparC is a subunit of the DNA topoisomerase IV and is sensitive to fluoroquinolone.
Drug Classfluoroquinolone antibiotic
Classification4 ontology terms | Show
Parent Term(s)7 ontology terms | Show
+ targeted_by_antibiotic ciprofloxacin [Antibiotic]
+ targeted_by_antibiotic levofloxacin [Antibiotic]
+ targeted_by_antibiotic ofloxacin [Antibiotic]
+ targeted_by_antibiotic norfloxacin [Antibiotic]
+ targeted_by_antibiotic pefloxacin [Antibiotic]
+ antibiotic sensitive DNA topoisomerase subunit parC
+ targeted_by fluoroquinolone antibiotic [Drug Class]
1 ontology terms | Show
+ fluoroquinolone resistant parC [AMR Gene Family] derives_from

Drlica K and Zhao X. 1997. Microbiol Mol Biol Rev 61(3): 377-392. DNA gyrase, topoisomerase IV, and the 4-quinolones. (PMID 9293187)