norfloxacin [Antibiotic]

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Accession ARO:3000662
DefinitionNorfloxacin is a 6-fluoro, 7-piperazinyl quinolone with a wide range of activity against Gram-negative bacteria. It is inactive against most anaerobes.
Drug Classfluoroquinolone antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
42 ontology terms | Show
+ fluoroquinolone sensitive parC targeted_by_antibiotic
+ fluoroquinolone sensitive gyrA targeted_by_antibiotic
+ norA confers_resistance_to_antibiotic
+ norB confers_resistance_to_antibiotic
+ pmrA confers_resistance_to_antibiotic
+ QepA1 confers_resistance_to_antibiotic
+ PatA-PatB confers_resistance_to_antibiotic
+ MdtEF-TolC confers_resistance_to_antibiotic
+ MexGHI-OpmD confers_resistance_to_antibiotic
+ Staphylococcus aureus norA confers_resistance_to_antibiotic
+ quinolone resistance protein (qnr) [AMR Gene Family] confers_resistance_to_antibiotic
+ MexXY-OprM confers_resistance_to_antibiotic
+ Bartonella bacilliformis gyrA conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Escherichia coli gyrA conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Mycobaterium leprae gyrA conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Staphylococcus aureus gyrA conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Morganella morganii gyrB conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Mycobacterium leprae gyrB conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Salmonella serovars gyrB conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Ureaplasma urealyticum gyrB conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Escherichia coli parC conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Mycoplasma hominis parC conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Staphylococcus aureus parC conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Streptococcus pneumoniae parC conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Ureaplasma urealyticum parC conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Escherichia coli parE conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Salmonella serovars parE conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Staphylococcus aureus parE conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Acinetobacter baumannii gyrA conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Acinetobacter baumannii parC conferring resistance to fluoroquinolone confers_resistance_to_antibiotic
+ Shigella flexneri gyrA conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ Shigella flexneri parC conferring resistance to fluoroquinolones confers_resistance_to_antibiotic
+ hmrM confers_resistance_to_antibiotic
+ MexEF-OprN with MvaT deletion conferring resistance to chloramphenicol and norfloxacin confers_resistance_to_antibiotic
+ QepA2 confers_resistance_to_antibiotic
+ mdtH confers_resistance_to_antibiotic
+ MexXY-OprA confers_resistance_to_antibiotic
+ Klebsiella pneumoniae KpnGH-TolC confers_resistance_to_antibiotic
+ abeM confers_resistance_to_antibiotic
+ mdtM confers_resistance_to_antibiotic
Publications

Holmes B, et al. 1985. Drugs 30(6): 482-513. Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. (PMID 3908074)