mupirocin [Drug Class]

Download Sequences


Accession ARO:3000554
Synonym(s)pseudomonic acid
DefinitionMupirocin, also known as pseudomonic acid, is a bacteriostatic polyketide antibiotic from Pseudomonas fluorescens used to treat S. aureus and MRSA. It inhibits Ile tRNA synthetase.
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
6 ontology terms | Show
+ determinant of mupirocin resistance confers_resistance_to_drug_class
+ antibiotic resistant isoleucyl-tRNA synthetase (ileS) [AMR Gene Family] confers_resistance_to_drug_class
+ Staphylococcus mupA conferring resistance to mupirocin confers_resistance_to_antibiotic
+ Staphylococcus mupB conferring resistance to mupirocin confers_resistance_to_antibiotic
+ Bifidobacterium ileS conferring resistance to mupirocin confers_resistance_to_antibiotic
+ antibiotic sensitive Isoleucyl-tRNA transferase targeted_by_antibiotic
Publications

Gurney R and Thomas CM. 2011. Appl Microbiol Biotechnol 90(1): 11-21. Mupirocin: biosynthesis, special features and applications of an antibiotic from a gram-negative bacterium. (PMID 21336932)