Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:3000635 |
Synonym(s) | dicloxacilin dicloxacycline |
Definition | Dicloxacillin is a penicillin derivative that has an extra chlorine atom in comparison to cloxacillin. While more active than cloxacillin, its high affinity for serum protein reduces its activity in human serum in vitro. |
SMILES | Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)O |
PubChem | 18381 |
ChEMBL | CHEMBL893 |
ChEBI | 4511 |
CAS | 3116-76-5 |
Drug Class | penicillin beta-lactam |
Classification | 4 ontology terms | Show |
Parent Term(s) | 1 ontology terms | Show |
Sub-Term(s) | 1 ontology terms | Show + beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic |
Publications | Bergdahl S, et al. 1987. Pharmacol Toxicol 60(3): 233-234. Plasma concentration following oral administration of di- and flucloxacillin in infants and children. (PMID 3588519) Lofgren S, et al. 1986. Scand J Infect Dis 18(4): 365-369. Single-dose pharmacokinetics of dicloxacillin in healthy subjects of young and old age. (PMID 3764352) |
Curator | Description | Most Recent Edit |
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