cycloserine sensitive D-alanine synthetase

Accession ARO:3000723
DefinitionD-Alanine synthetase (or ligase), also known as ddla, joins two D-alanines before their addition to the pentapeptide chains of peptidoglycan. It is found in both Gram-positive and Gram-negative bacteria.
Classification2 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ cell wall synthesis enzyme targeted by antibiotic
+ targeted_by_antibiotic cycloserine [Antibiotic]
Sub-Term(s)
1 ontology terms | Show
Publications

NEUHAUS FC and LYNCH JL. 1962. Biochem Biophys Res Commun 8: 377-382. Studies on the inhibition of D-alanyl-D-alanine synthetase by the antibiotic D-cycloserine. (PMID 14479178)