cell wall synthesis enzyme targeted by antibiotic

Accession ARO:3000709
DefinitionCell wall biosynthesis provides bacteria with a layer of peptidoglycan that provides rigidity and protects the cell from lysis due to osmotic pressure. Cell wall structures vary significantly between Gram-positive and Gram-negative bacteria, while mycobacteria have a unique cell wall composition.
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Bugg TD and Walsh CT. 1992. Nat Prod Rep 9(3): 199-215. Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance. (PMID 1436736)