Accession | ARO:3000725 |
Definition | Arabinofuranosyltransferases allow for the polymerization of arabinose to form arabinan. Arabanan is required for formation of mycobacterial cell walls. |
Classification | 2 ontology terms | Show |
Parent Term(s) | 2 ontology terms | Show + cell wall synthesis enzyme targeted by antibiotic + targeted_by_antibiotic ethambutol [Antibiotic] |
Sub-Term(s) | 7 ontology terms | Show + antibiotic sensitive embC + antibiotic sensitive embA + antibiotic sensitive embB + Antibiotic sensitive embR + ethambutol resistant aftA [AMR Gene Family] derives_from + antibiotic resistant aftA derives_from + rifamycin-resistant arabinosyltransferase [AMR Gene Family] derives_from |
Publications | Goude R, et al. 2009. Antimicrob Agents Chemother 53(10): 4138-4146. The arabinosyltransferase EmbC is inhibited by ethambutol in Mycobacterium tuberculosis. (PMID 19596878) Amin AG, et al. 2008. Microbiology 154(PT 1): 240-248. EmbA is an essential arabinosyltransferase in Mycobacterium tuberculosis. (PMID 18174142) |