antibiotic sensitive aftA

Accession ARO:3000725
DefinitionArabinofuranosyltransferases allow for the polymerization of arabinose to form arabinan. Arabanan is required for formation of mycobacterial cell walls.
Classification2 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ cell wall synthesis enzyme targeted by antibiotic
+ targeted_by_antibiotic ethambutol [Antibiotic]
7 ontology terms | Show

Goude R, et al. 2009. Antimicrob Agents Chemother 53(10): 4138-4146. The arabinosyltransferase EmbC is inhibited by ethambutol in Mycobacterium tuberculosis. (PMID 19596878)

Amin AG, et al. 2008. Microbiology 154(PT 1): 240-248. EmbA is an essential arabinosyltransferase in Mycobacterium tuberculosis. (PMID 18174142)