ethambutol resistant aftA [AMR Gene Family]

Accession ARO:3002876
DefinitionArabinofuranosyltransferases allow for the polymerization of arabinose to form arabinan. Arabinan is required for formation of mycobacterial cell walls and arabinosyltransferases are targets of the drug ethambutol. Mutations in these genes can confer resistance to ethambutol.
Drug Classpolyamine antibiotic
Resistance Mechanismantibiotic target alteration
Classification8 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ derives_from antibiotic sensitive aftA
+ antibiotic resistant aftA
+ confers_resistance_to_antibiotic ethambutol [Antibiotic]
+ confers_resistance_to_drug_class polyamine antibiotic [Drug Class]
1 ontology terms | Show