mecillinam [Antibiotic]

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Accession ARO:3000761
Synonym(s)amdinocillin Selexid Selexidin
DefinitionMecillinam is a broad-spectrum beta-lactam antibiotic that was semi-synthetically derived to have a different drug centre, being a 6-alpha-amidinopenicillanate instead of a 6-alpha-acylaminopenicillanate. Contrasting most beta-lactam drugs, mecillinam is most active against Gram-negative bacteria. It binds specifically to penicillin binding protein 2 (PBP2).
Drug Classpenam
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ penam [Drug Class]
1 ontology terms | Show

[Editors]. 1983. Am J Med 75(2A): 1-138. An international review of amdinocillin: a new beta-lactam antibiotic. (PMID 6310995)