efrotomycin [Antibiotic]

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Accession ARO:3001236
DefinitionEfrotomycin is produced by Streptomyces lactamodurans NRRL 3802. This kirromycin-like antibiotic is used in animal agriculture, especially in the production of swine. Generally gram negative bacteria are susceptible to efrotomycin, while gram positive bacteria are resistant.
Drug Classelfamycin antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show

Sarmah AK, et al. 2006. Chemosphere 65(5): 725-759. A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. (PMID 16677683)

Wax R, et al. 1976. J Antibiot (Tokyo) 29(6): 670-673. Efrotomycin, a new antibiotic from Streptomyces lactamdurans. (PMID 950325)

Landini P, et al. 1993. J Gen Microbiol 139(4): 769-774. Sensitivity of elongation factor Tu (EF-Tu) from different bacterial species to the antibiotics efrotomycin, pulvomycin and MDL 62879. (PMID 8515234)

Landini P, et al. 1992. Biochem J 283(PT 3): 649-652. Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin. (PMID 1590753)