phenelfamycin F [Antibiotic]

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Accession ARO:3001256
DefinitionPhenelfamycin F was isolated from two environmental isolates called AB999F-80 and AB1047T-33. They were both identified as Streptomyces violaceoniger strains. Both these strains were found to produce phenelfamycins A-F and unphenelfamycin. Phenelfamycin F has a trisaccaride moeity and is isomeric with phenelfamycin E. All phenelfamycins were selected due to their activity against anaerobic bacteria, especially Clostridioides difficile. Phenelfamycin E and F are the most potent of the phenelfamycins.
Drug Classelfamycin antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Publications

Hochlowski JE, et al. 1988. J Antibiot (Tokyo) 41(10): 1300-1315. Phenelfamycins, a novel complex of elfamycin-type antibiotics. II. Isolation and structure determination. (PMID 3192490)

Swanson RN, et al. 1989. J Antibiot (Tokyo) 42(1): 94-101. Phenelfamycins, a novel complex of elfamycin-type antibiotics. III. Activity in vitro and in a hamster colitis model. (PMID 2921230)

Jackson M, et al. 1988. J Antibiot (Tokyo) 41(10): 1293-1299. Phenelfamycins, a novel complex of elfamycin-type antibiotics. I. Discovery, taxonomy and fermentation. (PMID 3192489)