| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3001315 |
| Definition | Two semi-synthetic pleuromutilin derivatives, tiamulin and valnemulin, have been developed as antibiotics for veterinary use. |
| SMILES | C=C[C@]1(C)C[C@@H](OC(=O)CSC(C)(C)CNC(=O)[C@H](N)C(C)C)[C@]2(C)[C@H](C)CC[C@]3(CCC(=O)[C@H]32)[C@@H](C)[C@@H]1O |
| PubChem | 9850878 |
| CAS | 101312-92-9 |
| ChEBI | 29705 |
| ChEMBL | CHEMBL1688852 |
| Drug Class | pleuromutilin antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + pleuromutilin antibiotic [Drug Class] |
| Sub-Term(s) | 2 ontology terms | Show + vga(E) Staphylococcus cohnii confers_resistance_to_antibiotic + vgaC confers_resistance_to_antibiotic |
| Publications | Tang YZ, et al. 2012. Mini Rev Med Chem 12(1): 53-61. Pleuromutilin and its derivatives-the lead compounds for novel antibiotics. (PMID 22070694) Poulsen SM, et al. 2001. Mol Microbiol 41(5): 1091-1099. The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome. (PMID 11555289) |
| Curator | Description | Most Recent Edit |
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