cat

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Accession ARO:3002670
CARD Short Namecat
Definitioncat is used to describe many variants of the chloramphenicol acetyltransferase gene in a range of organisms including Acinetobacter calcoaceticus, Agrobacterium tumefaciens, Alkalihalobacillus clausii, Bacillus subtilis, Campylobacter coli, Enterococcus faecalis, Enterococcus faecium, Lactococcus lactis, Listeria monocytogenes, Listonella anguillarum Morganella morganii, Photobacterium damselae subsp. piscicida, Proteus mirabilis, Salmonella typhi, Serratia marcescens, Shigella flexneri, Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus intermedius, Streptococcus agalactiae, Streptococcus suis and Streptomyces acrimycini.
AMR Gene Familychloramphenicol acetyltransferase (CAT)
Drug Classphenicol antibiotic
Resistance Mechanismantibiotic inactivation
Classification8 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ chloramphenicol acetyltransferase (CAT) [AMR Gene Family]
+ confers_resistance_to_antibiotic chloramphenicol [Antibiotic]
Publications

Schwarz S, et al. 1991. Antimicrob Agents Chemother 35(8): 1551-1556. Nucleotide sequence and phylogeny of a chloramphenicol acetyltransferase encoded by the plasmid pSCS7 from Staphylococcus aureus. (PMID 1929326)

Cardoso M, et al. 1992. J Appl Bacteriol 72(4): 289-293. Nucleotide sequence and structural relationships of a chloramphenicol acetyltransferase encoded by the plasmid pSCS6 from Staphylococcus aureus. (PMID 1517170)

Tennigkeit J, et al. 1991. Gene 98(1): 113-116. Nucleotide sequence analysis of a chloramphenicol-resistance determinant from Agrobacterium tumefaciens and identification of its gene product. (PMID 2013403)

Projan SJ, et al. 1985. Mol Gen Genet 199(3): 452-464. Comparative sequence and functional analysis of pT181 and pC221, cognate plasmid replicons from Staphylococcus aureus. (PMID 2993795)

Perreten V, et al. 1997. Nature 389(6653): 801-802. Antibiotic resistance spread in food. (PMID 9349809)

Charles IG, et al. 1985. J Bacteriol 164(1): 123-129. Nucleotide sequence analysis of the cat gene of Proteus mirabilis: comparison with the type I (Tn9) cat gene. (PMID 3900035)

Trieu-Cuot P, et al. 1992. Plasmid 28(3): 272-276. Nucleotide sequence of the chloramphenicol resistance determinant of the streptococcal plasmid pIP501. (PMID 1461942)

Luck SN, et al. 2001. Infect Immun 69(10): 6012-6021. Ferric dicitrate transport system (Fec) of Shigella flexneri 2a YSH6000 is encoded on a novel pathogenicity island carrying multiple antibiotic resistance genes. (PMID 11553538)

Elisha BG, et al. 1991. Plasmid 25(2): 96-104. Identification of an Acinetobacter baumannii gene region with sequence and organizational similarity to Tn2670. (PMID 1650008)

Schwarz S, et al. 1991. J Gen Microbiol 137(4): 977-981. Cloning and sequence analysis of a plasmid-encoded chloramphenicol acetyltransferase gene from Staphylococcus intermedius. (PMID 1713259)

Bhakta M, et al. 2003. Curr Microbiol 46(6): 413-417. Identification and characterization of a shuttle plasmid with antibiotic resistance gene from Staphylococcus aureus. (PMID 12732947)

Goodner B, et al. 2001. Science 294(5550): 2323-2328. Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58. (PMID 11743194)

Aoki T, et al. 1987. Gene 51(1): 107-111. Complete nucleotide sequence of pTZ12, a chloramphenicol-resistance plasmid of Bacillus subtilis. (PMID 3110008)

Brenner DG and Shaw WV. 1985. EMBO J 4(2): 561-568. The use of synthetic oligonucleotides with universal templates for rapid DNA sequencing: results with staphylococcal replicon pC221. (PMID 3860383)

Schwarz FV, et al. 2001. Plasmid 46(3): 170-187. Sequence of the 50-kb conjugative multiresistance plasmid pRE25 from Enterococcus faecalis RE25. (PMID 11735367)

Galopin S, et al. 2009. FEMS Microbiol Lett 296(2): 185-189. A chromosomal chloramphenicol acetyltransferase determinant from a probiotic strain of Bacillus clausii. (PMID 19459958)

Schwarz S, et al. 1991. Antimicrob Agents Chemother 35(7): 1277-1283. Molecular cloning, purification, and properties of a plasmid-encoded chloramphenicol acetyltransferase from Staphylococcus haemolyticus. (PMID 1929282)

Horinouchi S and Weisblum B. 1982. J Bacteriol 150(2): 815-825. Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance. (PMID 6950931)

Zhao J, et al. 1992. Microbiol Immunol 36(7): 695-705. Cloning and nucleotide sequence analysis of a chloramphenicol acetyltransferase gene from Vibrio anguillarum. (PMID 1406372)

Wang Y and Taylor DE. 1990. Gene 94(1): 23-28. Chloramphenicol resistance in Campylobacter coli: nucleotide sequence, expression, and cloning vector construction. (PMID 2227449)

Takamatsu D, et al. 2003. Plasmid 49(2): 143-151. Chloramphenicol resistance transposable element TnSs1 of Streptococcus suis, a transposon flanked by IS6-family elements. (PMID 12726767)

Bruckner R and Matzura H. 1985. EMBO J 4(9): 2295-2300. Regulation of the inducible chloramphenicol acetyltransferase gene of the Staphylococcus aureus plasmid pUB112. (PMID 3865770)

Grady R, et al. 2003. Mol Microbiol 47(5): 1419-1432. Axe-Txe, a broad-spectrum proteic toxin-antitoxin system specified by a multidrug-resistant, clinical isolate of Enterococcus faecium. (PMID 12603745)

Murray IA, et al. 1989. Gene 85(2): 283-291. Nucleotide sequence of the chloramphenicol acetyltransferase gene of Streptomyces acrimycini. (PMID 2697637)

Parkhill J, et al. 2001. Nature 413(6858): 848-852. Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. (PMID 11677608)