Accession | ARO:3002682 |
CARD Short Name | catD |
Definition | catD is a chromosome and transposon-encoded variant of the cat gene found in Clostridioides difficile. |
AMR Gene Family | chloramphenicol acetyltransferase (CAT) |
Drug Class | phenicol antibiotic |
Resistance Mechanism | antibiotic inactivation |
Classification | 8 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + determinant of antibiotic resistance + antibiotic molecule + antibiotic inactivation [Resistance Mechanism] + antibiotic inactivation enzyme + phenicol antibiotic [Drug Class] + acylation of antibiotic conferring resistance |
Parent Term(s) | 4 ontology terms | Show + chloramphenicol acetyltransferase (CAT) [AMR Gene Family] + confers_resistance_to_antibiotic azidamfenicol [Antibiotic] + confers_resistance_to_antibiotic chloramphenicol [Antibiotic] + confers_resistance_to_antibiotic thiamphenicol [Antibiotic] |
Publications | Lyras D, et al. 2000. Mol Microbiol 38(3): 588-601. Transposition of Tn4451 and Tn4453 involves a circular intermediate that forms a promoter for the large resolvase, TnpX. (PMID 11069682) |