Accession | ARO:3003466 |
Definition | GidB is a m7G methyltransferase specific for 16S rRNA. Mutations within the gidB gene causes changes in the structure or 16s rRNA, leading to resistance to aminoglycosides. |
Drug Class | aminoglycoside antibiotic |
Resistance Mechanism | antibiotic target alteration |
Classification | 9 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + antibiotic target alteration [Resistance Mechanism] + determinant of antibiotic resistance + ribosomal alteration conferring antibiotic resistance + antibiotic target modifying enzyme + mutation conferring antibiotic resistance + rRNA methyltransferase conferring antibiotic resistance + antibiotic molecule |
Parent Term(s) | 4 ontology terms | Show + antibiotic resistant gene variant or mutant + confers_resistance_to_drug_class aminoglycoside antibiotic [Drug Class] + derives_from antibiotic sensitive gidB + 16S ribosomal RNA methyltransferase |
Sub-Term(s) | 1 ontology terms | Show |