aminocoumarin resistant alaS [AMR Gene Family]

Accession ARO:3003830
Definitionalanyl-tRNA synthetase conferring resistance to novobiocin in Escherichia coli
Drug Classaminocoumarin antibiotic
Resistance Mechanismantibiotic target alteration
Classification7 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ antibiotic resistant gene variant or mutant
+ confers_resistance_to_drug_class aminocoumarin antibiotic [Drug Class]
+ confers_resistance_to_antibiotic novobiocin [Antibiotic]
+ determinant of aminocoumarin resistance
Publications

Jovanovic M, et al. 1999. J. Bacteriol. 181(9):2979-83 tRNA synthetase mutants of Escherichia coli K-12 are resistant to the gyrase inhibitor novobiocin. (PMID 10217798)