aminocoumarin resistant cysB [AMR Gene Family]

Accession ARO:3003840
DefinitionPositive regulator of gene expression in the cysteine regulon. cysB mutants confer resistance to novobiocin, an aminocoumarin antibiotic, in Escherichia coli.
Drug Classaminocoumarin antibiotic
Resistance Mechanismantibiotic target alteration
Classification7 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ antibiotic resistant gene variant or mutant
+ confers_resistance_to_drug_class aminocoumarin antibiotic [Drug Class]
+ confers_resistance_to_antibiotic novobiocin [Antibiotic]
+ determinant of aminocoumarin resistance
Publications

Rakonjac J, et al. 1991. Mol. Gen. Genet. 228(1-2):307-11 cysB and cysE mutants of Escherichia coli K12 show increased resistance to novobiocin. (PMID 1886615)