tedizolid [Antibiotic]

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Accession ARO:3003897
DefinitionTedizolid is a synthetic oxazolidinone antibiotic that is administered to the patient as a prodrug that is activated in vivo. It acts as an inhibitor of protein synthesis by binding the 50S subunit of the ribosome and preventing formation of the 70S initiation complex. It is active against Gram-positive pathogens.
Drug Classoxazolidinone antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show
+ optrA confers_resistance_to_antibiotic

Kanafani ZA, et al. 2012. Expert Opin Investig Drugs 21(4):515-22 Tedizolid (TR-701): a new oxazolidinone with enhanced potency. (PMID 22324973)

Tatarkiewicz J, et al. 2016. Arch Med Sci 12(6):1327-1336 New agents approved for treatment of acute staphylococcal skin infections. (PMID 27904526)