Gamma-hemolysin (HlgAB)

Accession VIRO:0000047
Definitiongamma-hemolysin is a type of bi-component toxin produced by Staphylococcus aureus. Each of these toxins is made as two non-associated secreted proteins, referred to as S and F components. The gene of γ-hemolysin produces 2 S components (HlgA and HlgC) and 1 F component (HlgB). These three genes creates two functional gamma-hemolysins which are HlgAB and HlgCB. HlgAB is also a potent hemolysin in addition to its leukocidin activity
Classification11 ontology terms | Show
Parent Term(s)2 ontology terms | Show
2 ontology terms | Show
+ HlgA part_of
+ HlgB part_of

Dinges MM, et al. 2000. Clin. Microbiol. Rev. 13(1):16-34, table of contents Exotoxins of Staphylococcus aureus. (PMID 10627489)

Ferreras M, et al. 1998. Biochim. Biophys. Acta 1414(1-2):108-26 The interaction of Staphylococcus aureus bi-component gamma-hemolysins and leucocidins with cells and lipid membranes. (PMID 9804914)