loracarbef [Antibiotic]

Download Sequences


Accession ARO:3004016
Synonym(s)Loracarbefum Lorabid
DefinitionLoracarbef is a second-generation cephalosporin (carbacephem) and broad spectrum beta-lactam antibiotic. Loracarbef inhibits PBPs through binding, disrupting peptidoglycan cell wall cross-linkage and resulting in cell death.
Drug Classcephalosporin
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ cephalosporin [Drug Class]
Sub-Term(s)
1 ontology terms | Show
Publications

Jones RN, et al. 1987. Eur. J. Clin. Microbiol. 6(5):570-1 Beta-lactamase hydrolysis and inhibition studies of the new 1-carbacephem LY163892. (PMID 3501757)

Force RW, et al. 1993. Ann Pharmacother 27(3):321-9 Loracarbef: a new orally administered carbacephem antibiotic. (PMID 8453172)