loracarbef [Antibiotic]

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Accession ARO:3004016
Synonym(s)Lorabid Loracarbefum
DefinitionLoracarbef is a second-generation cephalosporin (carbacephem) and broad spectrum beta-lactam antibiotic. Loracarbef inhibits PBPs through binding, disrupting peptidoglycan cell wall cross-linkage and resulting in cell death.
Drug Classcephalosporin
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ cephalosporin [Drug Class]
1 ontology terms | Show

Jones RN, et al. 1987. Eur. J. Clin. Microbiol. 6(5):570-1 Beta-lactamase hydrolysis and inhibition studies of the new 1-carbacephem LY163892. (PMID 3501757)

Force RW, et al. 1993. Ann Pharmacother 27(3):321-9 Loracarbef: a new orally administered carbacephem antibiotic. (PMID 8453172)