balofloxacin [Antibiotic]

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Accession ARO:3004130
Synonym(s)Q-35 Q 35 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methylaminopiperidine-1-yl)-4-oxoquinoline-3-carboxylic acid
DefinitionBalofloxacin is an 8-methoxy fluoroquinolone antibiotic. It shows potent bactericidal activity and inhibits the supercoiling activity of DNA gyrase of S. aureus, E. coli, and P. aeruginosa.
Drug Classfluoroquinolone antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
1 ontology terms | Show
+ Escherichia coli LamB confers_resistance_to_antibiotic
Publications

Ito T, et al. 1992. Antimicrob. Agents Chemother. 36(8):1708-14 In vitro antibacterial activity of Q-35, a new fluoroquinolone. (PMID 1329626)

Ito T, et al. 1995. Antimicrob. Agents Chemother. 39(7):1522-5 Improved bactericidal activity of Q-35 against quinolone-resistant staphylococci. (PMID 7492097)