antibiotic sensitive dihydrofolate synthase

Accession ARO:3004156
DefinitionWild-type form of dihydrofolate synthase (synthetase) enzymes. Bioactivation of p-aminosalicylic acid occurs during the folate pathway when dihydrofolate and its analog hydroxyl-dihydrofolate are produced by dihydrofolate synthase. Disruption of this pathway by PAS results in cell damage and death.
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show
+ aminosalicylate resistant dihydrofolate synthase [AMR Gene Family] derives_from