phenotypic variant regulator [AMR Gene Family]

Accession ARO:3004286
DefinitionPhenotypic variant regulator proteins play a role in controlling the switch between antibiotic-susceptible and antibiotic-resistant forms of bacteria. The characterized member of this family is the PvrR protein in Pseudomonas aeruginosa, which when absent, confers antibiotic resistance.
Drug Classaminoglycoside antibiotic
Resistance Mechanismresistance by absence
Classification5 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class aminoglycoside antibiotic [Drug Class]
+ gene conferring resistance via absence
1 ontology terms | Show
+ PvrR

Wei Q, et al. 2011. PLoS ONE 6(12):e29276 Phenotypic and genome-wide analysis of an antibiotic-resistant small colony variant (SCV) of Pseudomonas aeruginosa. (PMID 22195037)